Burke Rosen

Burke Rosen

Hey there. I'm a neurosciences Ph.D. candidate in the lab of Prof. Eric Halgren at UC San Diego. My research is mainly focused on the structure and function of the hominin cortex, perhaps the most complex object in the universe. I examine the structural connections that underpin corticocortical communication using diffusion MRI and the functional correlativity that is its hallmark by compositing spontaneous activity from intracranial depth electrode recordings in hundreds of patients with drug-resistant epilepsy. My hope is that a better understanding of the full map of cortical communication can be leveraged to improve non-invasive neuroimaging technologies like EEG and MEG.

In addition to my primary lines of inquiry, I have some tangentially-related projects looking at the transcriptional markers of evolutionarily-recent cortical expansion and producing synthetic M/EEG, as well as an older series of work investigating acute alcohol intoxication and executive function with MEG. More broadly, I'm interested in data-driven approaches to observing the human brain's structure and function as it exists in its natural environment.

I'll be graduating soon and will then begin post-doctoral training with Profs. David Van Essen and Matthew Glasser at Washington University.

Select Publications

  • Rosen BQ, Halgren E (2022) An estimation of the absolute number of axons indicates that human cortical areas are sparsely connected. PLOS Biology 20(3): e3001575. Open Access, EurekAlert!, neurosciencenews
  • Rosen BQ, Halgren E (2021) A Whole-Cortex Probabilistic Diffusion Tractography Connectome. eNeuro 8(1):ENEURO.0416-20.202. Open Access
  • Dickey CW, Verzhbinsky IA, Jiang X, Rosen BQ, Kajfez S, Stedelin B, Shih JJ, Ben-Haim S, Raslan AM, Eskandar EN, Gonzalez-Martinez J, Cash SS, Halgren E. Widespread ripples synchronize human cortical activity during sleep, waking, and memory recall. (2022) PNAS Open Access

  • All publications

Downloadable Data & Resources

  • Whole cortex diffusion MRI connectivity matrices for 1,065 individuals of the WU-Minn Human Connectome Project cohort in the Glasser 360 parcellation
  • An estimation of the number of axons in the above connectivity matrices.
  • A two lecture introduction to basic digital signal processing for neuroscience, originally for a student-run course, with accompanying quizes and problem sets. Sorry about the pre-pandemic audio quality.

Fun Facts

  • The weekly electric elephantnose fish has the largest brain-to-body oxygen use ratio of all vertebrates. I tried to keep one in the lab aquarium, but was unsuccessful.
  • A primitive EEG system can be cobbled together from an Arduino and $35 mattel toy.
  • I've been to all 58 of my home state of California's counties.
  • According to Neurotree, there are 88 generations of mentor-mentee relationships in the direct line of decent from John the Baptist to me. Notable links in the chain include Charles Sherrington and Albertus Magnus. "If I have seen further it is by standing on the shoulders of giants."




mindBlown

where action meets potential
-UCSD NGP-





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